Ultra Filter System is applied in downstream purification and separation of biological products, removal of endotoxins in injections, desalination of small nucleic acid products, and solvent removal in the peptide industry, it can provide concentration and liquid exchange functions, as well as clarification and microfiltration. The filtration elements can be in the form of hollow fibers or membrane cartridges, and can also flexibly switch between ultrafiltration and nano-filtration process.
System Features
· Customized systems based on client production requirements (with in-house testing capabilities);
· Online CIP cleaning function;
· Online SIP sterilization function (except for ultrafiltration membranes);
· Automatic preparation, storage, and cleaning of membrane soaking solutions;
· Automatic water flux NWP testing function;
· Automatic implementation of multiple control modes such as TMP, feed flow rate, ΔP, and fixed pump speed, with custom control logic available upon request;
· Online integrity testing of membrane packages and generation related test reports;
· Precise temperature control function (especially crucial for protein, peptide, and small nucleic acid products, and also helpful for achieving better NWP);
· Flexible cleaning, sterilization, and production process combinations through PLC or DCS;
· Provision of 1:1 3D design models to meet operation, maintenance, and repair needs, while saving space;
· CGMP-compliant automated control system (PLC);
· DQ/IQ/OQ/RA/CCA/RTM and other validation works.
Keywords:
Welkin
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